Selected Publications

 

 

1.      Synthesis of 1,4-Diketones by Palladium-Catalyzed reductive Coupling of Acid Chlorides with (E)-1,2-Bis(tri-n-butylstannyl)ethene or b-Stannnyl Enones.

Pérez, M.; Castaño, A. M.; Echavarren, A. M.

J. Org. Chem. 1992, 57, 5047 - 5049.

 

2.      Strategies for the Synthesis of Palladium Enolates and Homoenolates: Palladation of Ketone N,N-Dimethylhydrazones.

Cárdenas, D. J.; Echavarren, A. M.

Anales de Química 1993, 89, 107-110.

 

3.      Synthesis of Ru(II) Hydride and Alkenyl Amidine Complexes. The Crystal Structure of [Ru(CO)(CH=CHCMe3){NH=C(Me)(Me2pz)}(PPh3)2]PF6.

López, J.; Santos, A.; Romero, A.; Echavarren, A. M.

J. Organomet. Chem. 1993, 443, 221 - 228.

 

4.      Synthesis of Butenynylruthenium Complexes from Hydrido, Alkenyl or Alkynyl Complexes.

Santos, A.; López, J.; Matas, L.; Ros, J.; Galán, A.; Echavarren, A. M.

Organometallics 1993, 12, 4215 - 4218.

 

5.      Synthesis of Protected 3-Methylaspartic Acids from Glutamic Anhydride via Nickelacycles.

Castaño, A,. M.; Echavarren, A. M.

Tetrahedron Lett. 1993, 34, 4361 - 4362.

 

6.      Synthesis of the Benzo[b]carbazoloquinone with the Structure Proposed for Prekinamycin.

Echavarren, A. M.; Tamayo, N.; Paredes, M. C.

Tetrahedron Lett. 1993, 34, 4713 - 4716.

 

7.      Aliphatic Palladation of Ketone N,N-Dimethylhydrazones.

Cárdenas, D. J.; Echavarren, A. M.; Vegas, A.

Organometallics 1994, 13, 882 - 889.

 

8.      Reactivity of a Nickelacycle Derived from Aspartic Acid: Alkylations, Insertions, and Oxidations.

Castaño, A. M.; Echavarren, A. M.

Organometallics 1994, 13, 2262 - 2268.

 

9.      Palladium-Catalyzed Reductive Coupling of Acid Chlorides with b-Stannyl Enones: Synthesis of 1,4-Diketones and Mechanistic Aspects.

Echavarren, A. M.; Pérez, M.; Castaño, A. M.; Cuerva, J. M.

J. Org. Chem. 1994, 59, 4179 - 4185.

 

10.   Design and Synthetic Applications of New Heterometallacycles.

Echavarren, A. M.; Cárdenas, D. J.; Castaño, A. M.; Cuerva, J. M.; Mateo, C.

Bull. Soc. Chim. Belg. 1994, 103, 549 - 558.

 

11.   Synthesis of New Ruthenium(II) Carbonyl Hydrido, Alkenyl, and Alkynyl Complexes with Chelating Diphosphines.

Santos, A.; López, J.; Montoya, J.; Noheda, P.; Romero, A.; Echavarren, A. M.

Organometallics 1994, 13, 3605 - 3615.

 

12.   Formation of a,b-Unsaturated Carbonyl Compounds by Palladium-Catalyzed Oxidation of Allylic Alcohols.

Gómez-Bengoa, E.; Noheda, P.; Echavarren, A. M.

Tetrahedron Lett. 1994, 35, 7097 - 7098.

 

13.   Synthesis of Antibiotics WS5995 A and C and Related Compounds by Palladium-Catalyzed Coupling of 2-Bromonaphthoquinones with Organostannanes.

Echavarren, A. M.; Tamayo, N.; Cárdenas, D. J.

J. Org. Chem. 1994, 59, 6075 - 6083.

 

14.   A Concise Synthesis of (±)-Monomorine I by way of a Palladium-Catalyzed Reductive Coupling.

Castaño, A. M.; Cuerva, J. M.; Echavarren, A. M.

Tetrahedron Lett. 1994, 35, 7435 - 7438.

 

15.   Synthesis of Oxa- and Azapalladacycles from Organostannanes.

Cárdenas, D. J.; Mateo, C.; Echavarren, A. M.

Angew. Chem., Int. Ed. Engl. 1994, 33, 2445 – 2447; Angew. Chem. 1994, 106, 2529 - 2531.

 

16.   Synthesis of 3-Methylaspartic Acids by Ring-Contraction of a Nickelacycle Derived from Glutamic Anhydride.

Echavarren, A. M.; Castaño, A. M.

Tetrahedron 1995, 51, 2369-2378.

 

17.   Selectivity in the Aliphatic Palladation of Ketone Hydrazones. An Example of Palladium-Promoted Intramolecular Addition of a N,N-Dimethylhydrazone to an Alkene.

Cárdenas, D. J.; Echavarren, A. M.

Organometallics 1995, 14, 4427-4430.

 

18.   Calix[4]arene Sulfonates: Palladium-Catalyzed Intermolecular Migration of Sulfonyl Groups and Isolation of a Calix[4]arene in a Chiral 1,2-Alternate Conformation.

González, J. J.; Nieto, P. M.; Prados, P.; Echavarren, A. M.; de Mendoza, J.

J. Org. Chem. 1995, 60, 7419-7423.

 

19.   Palladium-Catalyzed Coupling of Allyl Carbonates with Stannanes.

Castaño, A. M.; Echavarren, A. M.

Tetrahedron Lett. 1996, 37, 6587-6590.

 

20.   Recent Developments in the Synthesis of Marine Pyridoacridine Alkaloids.

Echavarren, A. M.

Advances in Nitrogen Heterocycles, Vol. 2, Cap. 5; Moody, C. J. Ed.; JAI Press: Greenwich, 1996.

 

21.   Palladium-Switchable Bisnucleophiles.

Castaño, A. M.; Ruano, M.; Echavarren, A. M.

Tetrahedron Lett. 1996, 37, 6591-6594.

 

22.   Michael reaction of Stabilized Carbon Nucleophiles Catalyzed by [RuH2(PPh3)4].

Gómez-Bengoa, E.; Cuerva, J. M.; Mateo, C.; Echavarren. A. M.

J. Am. Chem. Soc. 1996, 118, 8553-8565.

 

23.   Syntheses of Phenanthroviridone, Gilvocarcin BE-12406X2, and Antibiotic WS 5995B Based on the Palladium and Copper Catalyzed Coupling of Organostannanes with Bromoquinones.

de Frutos, Ó.; Echavarren, A. M.

Tetrahedron Lett. 1996, 37, 8953-8956.

 

24.   Isolation of Transmetallation Intermediates in the Stille Cross-Coupling Reaction of Stannanes: Synthesis of Palladacycles, Ligand Substitution, and Insertion Reactions.

Mateo, C.; Cárdenas, D. J.; Fernández-Rivas, C.; Echavarren, A. M.

Chem. Eur. J. 1996, 2, 1596-1606.

 

25.   Synthesis of Heterocyclic Quinones by Aza-Diels-Alder Reaction of a 4-Stannyl-1-azadiene.

Cuerva, J. M.; Echavarren, A. M.

Synlett 1997, 173-174.

 

26.   Synthesis of Spiro Polycyclic Aromatic Hydrocarbons by Intramolecular Palladium-Catalyzed Arylation.

González, J. J.; García, N.; Gómez-Lor, B.; Echavarren, A. M

J. Org. Chem. 1997, 62, 1286-1291.

 

27.   Cationic Intermediates in the Intramolecular Insertion of Alkenes into (h3-Allyl)palladium(II) Complexes.

Gómez-Bengoa, E.; Manuel Cuerva, J.; Echavarren, A. M., Martorell, G.

Angew. Chem., Int. Ed. Engl. 1997, 36, 767-769; Angew. Chem. 1997, 109, 795-797.

 

28.   Isolation of the Transmetallation Step in the Hiyama Cross-Coupling of Organosilanes.

Mateo, C.; Fernández-Rivas, C.; Echavarren, A. M.; Cárdenas, D. J.

Organometallics 1997, 16, 1997-1999.

 

29.   The Effect of N-Donor Ligands on the Reaction of Ruthenium Hydrides with 1-Alkynes.

Santos, A.; López, J.; Galán, A.; González, J. J.; Tinoco, P.; Echavarren, A. M.

Organometallics 1997, 16, 3482-3488.

 

30.   Palladium-Catalyzed Synthesis of Tetraethynyl and Tetraethenyl Biphenyls: Elongated Tetrahedral Tectons.

Gómez-Lor, B.; Echavarren, A. M.; Santos, A.

Tetrahedron Lett. 1997, 38, 5347-5350.

 

31.   Palladium-Catalyzed Coupling of Naphthoquinone Triflates with Stannanes. Unprecedented Nucleophilic Aromatic Substitution on a Hydroxynaphthoquinone Triflate.

Echavarren, A. M.; Frutos, Ó.; Tamayo, N.; Noheda, P.; Calle, P.

J. Org. Chem. 1997, 62, 4524-4527.

 

32.   An Approach to the Synthesis of the Benzo[b]fluorene Core of the Kinamycins by an Arylalkyne-Allene Cycloaddition.

de Frutos, Ó.; Echavarren, A. M

Tetrahedron Lett. 1997, 38, 7941-7942.

 

33.   Synthesis of Benzo[b]carbazoloquinones by Coupling of Organostannanes with Bromoquinones.

Echavarren, A. M.; Tamayo, N.; de Frutos, Ó.; García, A.

Tetrahedron 1997, 53, 16835-16846.

 

34.   Synthesis of (±)-10-epi-Elemol by a Highly Stereoselective Intramolecular Coupling of an Allylstannane with an Allyl Acetate.

Cuerva, J. M.; Gómez-Bengoa, E.; Méndez, M.; Echavarren, A. M.

J. Org. Chem. 1997, 62, 7540-7541.

 

35.   Steric Hindrance Facilitated Synthesis of Enynes and Their Intramolecular [4+2] Cycloaddition with Alkynes.

González, J. J.; Francesch, A.; Cárdenas, D. J.; Echavarren, A. M.

J. Org. Chem. 1998, 63, 2845 - 2857.

 

36.   Intramolecular Transmetalation of Arylpalladium(II) and Arylplatinum(II) Complexes with Silanes and Stannanes.

Mateo, C.; Fernández-Rivas, C.; Cárdenas, D. J.; Echavarren, A. M.

Organometallics 1998, 17, 3661 - 3669.

 

37.   syn-Trialkylated Truxenes: Building Blocks which Self-Associate by Arene Stacking.

de Frutos, Ó.; Gómez-Lor, B.; Granier, T.; Monge, M. Á.; Gutiérrez-Puebla, E.; Echavarren, A. M.

Angew. Chem. Int. Ed. 1999, 38, 204 - 207; Angew. Chem. 1999, 111, 186 - 189.

 

38.   Direct Synthesis of N-Aryl Quinone Imine Acetals and Quinol Imines from Acetals.

Carreño, M. C.; Cuerva, J. M.; Ribagorda, M.; Echavarren, A. M.

Angew. Chem. Int. Ed. 1999, 38, 1449-1452; Angew. Chem. 1999, 111, 1552 - 1555.

 

39.   Divergent Behavior of Pd(II) and Pt(II) in the Matalation of 1,3-Di(2-pyridyl)benzene.

Cárdenas, D. J.; Echavarren, A. M.; Ramírez de Arellano, M. C.

Organometallics 1999, 18, 3337 - 3341.

 

40.   New Synthesis of Pyridoacridines Based on an Intramolecular Aza-Diels-Alder Reaction Followed by an Unprecedented Rearrangement.

Cuerva, J. M.; Cárdenas, D. J.; Echavarren, A. M.

Chem. Commun. 1999, 1721-1722.

 

41.   Intracluster Transmetalation of Cuprates with Stannanes.

Mateo, C.; Cárdenas, D. J.; Martín-Matute, B.; Echavarren, A. M.

Chem. Commun. 1999, 2205-2206.

 

42.   Synthesis of “Crushed Fullerene” C60H30.

Gómez-Lor, B. de Frutos, Ó.; Echavarren, A. M.

Chem. Commun. 1999, 2431-2432.

 

43.   Synthesis of Fullerene Fragments.

Echavarren, A. M.; Gómez-Lor, B.; de Frutos, Ó.

Proc. Electrochem. Soc. (2000), (Fullerenes 2000-Volume 9: Functionalized Fullerenes), 136-155.

 

44.   Metal-Catalyzed Carbocyclization by the Intramolecular Reaction of Allylsilanes and Allylstannanes with Alkynes.

Fernández-Rivas, C.; Méndez, M.; Echavarren, A. M.

J. Am. Chem. Soc. 2000, 122, 1221-1222.

 

45.   Palladium-Catalyzed Reaction of a Sterically Constrained Trialkyne: A Dimerization-type reaction with a Surprising Finale.

Granier, T.; Cárdenas, D. J.; Echavarren, A. M.

Tetrahedron Lett. 2000, 41, 6775-6779.

 

46.   Platinum-catalyzed Hydroxy- and Alkoxycyclization of Enynes.

Méndez, M.; Muñoz, M. P.; Echavarren, A. M.

J. Am. Chem. Soc. 2000, 122, 11549-11550.

 

47.   Nuevas síntesis de fragmentos de fullerenos.

Echavarren, A. M.; de Frutos, Ó.; Granier, T. Gómez-Lor, B.

Los Materiales Moleculares en España en el umbral del siglo XXI.

Vázquez, P.; Torres, T.; Martín, N., Eds.; UAM Ediciones; 2001, pp. 383-400.

 

48.   Synthesis of Benzo[b]phenanthridines and Related Naturally Occurring 2-Aryl-1,4-Naphthoquinones by the Palladium and Copper Catalyzed Coupling of Organostannanes with Bromoquinones

de Frutos, Ó.; Atienza, C.; Echavarren, A. M.

Eur. J. Org. Chem. 2001, 163-171

 

49.   Reaction of Vinyl Epoxides with Palladium-Switchable Bisnucleophiles: Synthesis of Carbocycles.

Castaño, A. M.; Méndez, M.; Ruano, M.; Echavarren, A. M.

J. Org. Chem. 2001, 66, 589-593.

 

50.   Formation of Benzo[b]fluorenes and the Benzo[a]fluorene Core of the Fluostatins by Cyclization of Diaryldiynones.

Atienza, C.; Mateo, C.; Frutos, Ó.; Echavarren, A. M.

Org. Lett. 2001, 3, 153-155.

 

51.   Intramolecular C-H Activation by Alkylpalladium(II) Complexes: Insights into the Mechanism of the Palladium-Catalyzed Arylation Reaction.

Martín-Matute, B.; Mateo, C.; Cárdenas, D. J.; Echavarren, A. M.

Chem. Eur. J. 2001, 7, 2341-2348.

 

52.   Synthesis of New C3v and C3h truxene Derivatives.

Gómez-Lor, B. de Frutos, Ó.; Ceballos, P. A.; Granier, T.; Echavarren, A. M.

Eur. J. Org. Chem. 2001, 2107-2114.

 

53.   New Palladacycles with a Pd-O Bond: Synthesis, Structure and Reactions.

Fernández-Rivas, C.; Cárdenas, D. J.; Monge, Á.; Gutiérrez-Puebla, E.; Echavarren, A. M.

Organometallics 2001, 20, 2998-3006..

 

54.   Palladacycles as Precatalysts in Heck and Cross-Coupling Reactions

Muñoz, M. P.; Martín-Matute, B.; Fernández-Rivas, C.; Cárdenas, D. J.; Echavarren, A. M.

Adv. Synt. & Catal. 2001, 343, 338-342.

 

55.   Ruthenium-Capping of Di- and Tetraethynylbiphenyls.

Gómez Lor, B.; Santos, A.; Ruiz, M.; Echavarren, A. M.

Eur. J. Inorg. Chem., 2001, 2305-2310.

 

56.   Cyclizations of Enynes Catalyzed by PtCl2 or Other Transition Metal Chlorides: Divergent Reaction Pathways

Méndez, M.; Muñoz, M. P.; Nevado, C.; Cárdenas, D. J.; Echavarren, A. M.

J. Am. Chem. Soc. 2001, 123, 10511-10520.

 

57.   Pt(II)-catalyzed Intramolecular Reaction of Furanes with Alkynes

Martín-Matute, B.; Cárdenas, D. J.; Echavarren, A. M.

Angew. Chem. Int. Ed. 2001, 40, 4754-4757; Angew. Chem. 2001, 113, 4890-4893.

 

58.   New Strategies for the Synthesis of Carbocycles Based on Transition-Metal Catalyzed Cyclization reactions of Organostannanes and Organosilanes.

Méndez, M.; Echavarren, A. M.

Eur. J. Org. Chem., 2002, 15-28.

 

59.   Zipping up ‘the crushed fullerene’ C60H30: C60 by fifteen-fold, consecutive intramolecular H2 losses.

Gómez-Lor, B.; Koper, C.; Fokkens, R. H.; Vlietstra, E. J.; Cleij T. J.;. Jenneskens, L. W.; Nibbering, N. M. M., Echavarren, A. M.

Chem. Commun. 2002, 370-371.

 

60.   Synthesis and Self-Association of syn-5,10,15-Trialkylated Truxenes.

de Frutos, Ó.; Granier, T.; Gómez-Lor, B.; Jiménez-Barbero, J.; Monge, A.; Gutiérrez-Puebla, E.; Echavarren, A. M.

Chem. Eur. J. 2002, 8, 2879-2890.

 

61.   Intramolecular Michael-type Addition of Azadienes to 1,4-Naphthoquinones instead of Aza-Diels-Alder Cycloaddition: A Synthesis of Ascididemin.

Cuerva, J. M.; Cárdenas, D. J.; Echavarren, A. M.

J. Chem. Soc., Perkin Trans. 1 2002, 1360-1365.

 

62.   Intramolecular Coupling of Allyl Carboxylates with Allylstannanes and Allylsilanes: A New Type of Reductive Elimination Reaction?

Méndez, M.; Cuerva, J. M.; Gómez-Bengoa, E.; Cárdenas, D. J.; Echavarren, A. M.

Chem. Eur. J. 2002, 8, in press.

 

63.   Reaction of Allylsilanes and Allylstannanes with Alkynes Catalyzed by Electrophilic Late Transition Metal Chlorides?

Fernández-Rivas, C.; Méndez, M.; Nieto-Oberhuber, C.; Echavarren A. M.

J. Org. Chem.  2002, 67, in press (jo025812n).

 

64.   Palladium-Catalyzed Intramolecular Arylation Reaction: Mechanism and Application for the Synthesis of Polyarenes

Echavarren A. M.; Gómez-Lor, B.; González, J. J.; Frutos, Ó. de

Synlett 2002, in press.