Pre-Op Evaluation and Premedications

       A. Communicating with the surgeon

       B. In addition to all the other things that are
          normally investigated during an anesthesia pre-
          op, the neuroanesthesiologist is interested in
          determining where on the intracranial
          compliance curve the patient is residing.

            1. The classic physical signs of increased
               ICP and decreased "compliance" include
               lethargy, disorientation, slurred speech,
               vomiting and headaches.

                 a. However, patients may be wide awake
                    and yet be at a point on the
                    compliance curve that is close to the
                    steep section, giving the patient very
                    little reserve. Knowledge of the CT
                    scan can help identify these patients.
                    

            2. Evaluate the CT scan for cerebral edema,
               midline shift, ventricular distortion and
               hydrocephalus to asses the ICP.  Induction
               technique and premedications will depend
               on the degree of intracranial reserve. 

       C. The general rule for premeds is "less is best".
          The lower the intracranial compliance, the less
          premed. The pt with an aneurysm is more heavly
          sedated than the tumor patient, giving due
          considertion to the ICP.

            1. Don't give long acting sedatives such as
               Ativan.

            2. More sedation, usually with fentanyl, may
               be given in the OR prior to plavcement of
               the A-Line

            3. Consider Benadryl or Vistaril at a dose of
               25 to 50 mg. IM or PO as a pre-op med. 

            4. Patients receiving phenobarbital on call to the
               O.R. as a continuation of their anticonvulsant
               regimen may become sedated with this
               alone, especially if given IV.

            5. Consider anticholinergics as a
               premedication in patients whose surgeries
               are known to cause strong vagal reflexes.
               These include glycerol rhizotomy and
               sterotactic brain biopsy.

       D. Continue anticonvulsants and note times
          that subsequent doses are to be given.

       E. Anticonvulsants, antibiotics, steroids,
          nimodipine, antihypertensives, cardiac meds,
          aminophyllin and thyroid supplements.

            1. Give the patient his normal morning dose
               of the above medications except for
               diuretics.

            2. Note the time of the last dose of
               anticonvulsants and steroids. Additional
               doses may need to be given later in the
               course of the operation. Steroids are
               usually ordered by the surgeon. Ask him
               about it if not ordered. If you feel
               steroids are necessary for adrenal
               insufficiency, give them.

            3. Nimodipine is generally given as already
               scheduled. It may be given with a sip of
               water on the AM of surgery if normally
               taken at that time.

                 a. Give consideration to an NG tube
                    rather than an OG tube for the patient
                    who will receive Nimodipine post-op.

            4. Antibiotics are often given in the OR at
               the start of the case.  They are too easy
               to forget. If they were not ordered, ask
               the surgeon if he wants them.  They are best
	       given BEFORE the surgeon makes first incision.

       F. Phenothiazines are avoided in neurosurgery
          because of their ability to lower the seizure
          threshold.  Tigan IM is the preferred agent.

       G. Be sure to write specific orders regarding which
	  maintenance meds are to be given on the morning
	  of surgery.  Be careful writing the order "take 
	  all meds with sip H2O". With this wording, only
          medications that the patient is due to receive
          prior to leaving for the OR will be given. For
          example, an antihypertensive scheduled for 7AM
          will not be given if the patient leaves for the
          OR at 6AM. Specify each drug and the time the
          drug is to be given.

       H. If the patient has a beard that will interfere
          with taping the ET tube, get his consent to
          shave it in the OR. A verbal, documented
          consent will do. Failing this, lots of tincture
	  of benzoin or Mastisol, with tape completely
	  around the head (assuming the surgeons aren't
	  using a porterior approach) will help.  Try to 
	  use the cheek bones, where there may be some 
	  exposed shin.

       I. Patients with a history of hypothyroidism
          should have thyroid function documented by a
	  set of thyroid funnction lab tests.  Consider
	  hypothyroidism in the differential of
          an unexplained hypotension under anesthesia.    

Monitor Selection