Chem. Eur. J. 2012, 18, 2773-2776. DOI: 10.1002/chem.201200108
Merging three in one by a three‐component organocatalytic asymmetric reaction of imines and α‐bromoesters or ketones with α,β‐unsaturated aldehydes provides optically active pyrrolo‐isoquinolines—an important class of molecules in life science. The reaction proceeds with excellent enantioselectivity and a number of transformations of the products obtained demonstrated the potential of the new reaction.
Destacado por Synfacts 2012, 8, 560
Universidad Autónoma de Madrid © 2008 · Ciudad Universitaria de Cantoblanco · 28049 Madrid · Información y Conserjería: 91 497 43 31 E-mail: informacion.ciencias@uam.es Gestión de estudiantes de Grado y Posgrado: 91 497 8264 / 4329 / 4353 / 4349 / 6879 / 8362 E-mail: administracion.ciencias@uam.es