Research Group: Neurobiology of the Inflammatory Response in Human Pathology

Applied research lines:

• Systemic inflammatory response in sepsis and in conditions of prolonged hypoxia/anoxia (cardiac arrest; acute coronary syndrome).
• Molecular mechanisms involved in the innate immune response.

Lines of study framed in basic research projects:

• Study of the pathophysiological role of nicotinic a7 and dupa7 receptors expressed in human macrophages, neurons and lung carcinoma cells.
• Identification of signalling pathways connecting nicotinic a7 receptors and negative regulators of TLR-mediated inflammation in human macrophages.