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Área de Psicobiología

Nombela Otero, Cristina

Nombela Otero, Cristina

Investigadora Postdoctoral Tomás y Valiente
Despacho:
114
Email:
cristina.nombela@uam.es
Teléfono:
91 497 5921
Resumen curriculum vitae

BIOGRAFÍA:

I am a neuropsychologist working for more than 15 years in understanding the cognitive disturbances in neurodegenerative diseases, like PD, which is a priority within the Horizon Europe program (European Union). My work has covered two main research lines: 1) Description of mechanisms underlying cognitive impairments in PD and healthy controls using Neuropsychological and Neuroimaging techniques; and 2) Treatment: Evaluation of pharmacological (norepinephrine and serotonin) and non-pharmacological tools (Cognitive training and surgical treatment) in Parkinson´s disease. My research has been performed in Spain, UK, Italy, & France, getting in contact with researchers from all around the world at international projects. In the recent years, I have achieved wide experience in grade and postgraduate teaching in both Spanish and English to students from Spain (UAM, UNED) and the USA (Univ. of Minnesota).

Publicaciones

Nombela, C., Giné, E., Sanz, C., Martínez, C. and de Castro, F. (2020). Laura Forster and Manuela Serra at the Cajal School. In WiNEu, European Women in Neuroscience, Untold stories: the Women Pioneers of Neuroscience in Europe. Retrieved from https://wineurope.eu/forster-serra-cajal-school/

Giné E, Nombela C, de Castro F. (2020). Las Científicas “olvidadas” de la Escuela de Cajal. Mente y Cerebro, Septiembre/Diciembre.

                     https://www.investigacionyciencia.es/revistas/cuadernos/cajal-810/las-cientficas-invisibles-de-la-escuela-de-cajal-19101

Esteban-Garcia N, Nombela C, Garrosa J, Rascón-Ramirez FJ, Barcia JA, Sánchez-Sánchez-Rojas L. Neurorestoration Approach by Biomaterials in Ischemic Stroke. Front Neurosci. 2020 May 12;14:431. doi: 10.3389/fnins.2020.00431.

Rascón-Ramirez FJ, Barcia JA, Nombela C* & Sánchez-Sánchez-Rojas* L. (2020) Cell therapy in ischemic stroke: How I do it?  Int Annals of Science (in press)

Nombela C, Giné E, De Castro F. (2021) Carmen Serra: A special case in Cajal's School. Neuroscience and History (in press).

Más información

Otra información de interés

Scientific Publications

Indexed Scientific papers

Malia D, Sánchez-Gascón F, Ros JA, Gómez M, Castell P, Nombela C, Méndez P, Abellán MC & Hernández J. (2005). Factores que influyen en el síndrome de apneas-hipoapneas durante el sueño. Med Clin (Barc) 125: 681-4

Barcia C, Ros F, Carrillo MA, Aguado-Llera D, Ros CM, Gómez A, Nombela C, de Pablos V, Fernández-Villalba E & Herrero MT. (2009) Inflammatory response in Parkinsonism. J Neural Transm Suppl 73: 245-52

Nombela C, Bustillo PJ, Castell PF, Sanchez L, García Medina V, Herrero MT. (2011) Cognitive rehabilitation in Parkinson’s disease: evidence from neuroimaging. Front Neurol 22; 2-82

Nombela C, Pedreño-Molina JL, Molina-Vilaplana J, Ros-Bernal F, Barcia C, López-Coronado J, Herrero MT. (2012) Dopamine modulation affects the performance of parkinsonian patients in a precision motor task measured by an anthropomorphic device. Hum Mov Sci 31, 730-42

Nombela C, Rae CL, Owen AM, Grahn J, Rowe J. (2013) How beneficial is rhythm stimulation for improving motor features in Parkinson’s disease? J Neurol 260: 1404-5

Nombela C & Nombela M. (2013) Is mu a normal rhythm? Orthop Muscul Syst 2:122

Nombela C (2013). Review of Textbook of Clinical Neuropsychiatry and Behavioural Neuroscience (3rd ed.) By DP Moore and BK Puri (864 pages). Taylor & Francis (Hodder Arnold): Abingdon, UK. Psychological Medicine, 43, Issue 11: 2459

Nombela C, Hughes LE, Owen AM, Grahn JA. (2013) Into the groove: can music influence motor deficits in Parkinson´s disease? Neurosci Biobehav Rev 37: 2564-70

Yarnall AJ, Breen DP, Duncan GW, Khoo TK, Coleman SY, Firbank MJ, Nombela C, Winder-Rhodes S, Evan JR, Rowe JB, Mollenhauer B, Kruse N, Hudson G, Chinnery PF, O’Brien JT, Robbins TW, Wesnes K, Brooks D, Barker RA, Burn DJ, on behalf of the ICICLE-PD study group. (2014) Characterising Mild Cognitive Impairment in Incident Parkinson’s Disease: The ICICLE-PD Study. Neurology 82: 308-16

Nombela C, Rittman T, Robbins TW, Rowe JB. (2014) Impulsivity in Parkinson’s disease: A multidimensional conceptualization. PLoS One 9(1):e85747

Ye Z, Altena E, Nombela C, Housden C, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB. (2014) Selective serotonin reuptake inhibition modulates impulsivity in Parkinson’s disease. Brain 137: 1145-55

Ye Z, Altena E, Nombela C, Housden C, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB. (2015) Improving response inhibition in Parkinson’s disease with Atomoxetine. Biol Psychiatry. 77: 740-8

Nombela C, Rowe J, Hampshire A, Owen A, Breen D, Khoo T, Firbank M, Yarnall A, Duncan G, O'Brien J, Burn D, Brooks D, Barker R. (2013) Spatial planning ability in early stage Parkinson’s disease patients (ICICLE-PD). Mov Disord, 27 (S1), S1–S523

Nombela C, Nombela M, Castell P, García T, López-Coronado J, Herrero MT. (2014) Alpha-Beta effects associated with ageing and the Stroop interference. PLoS One 9(5):e95657

Nombela C, Rowe JB, Firbank MJ, Winder-Rodes S, Hampshire A, Owen AM, Yarnall AJ, Breen P, Duncan GW, Khoo TK, Chinnery PF, O’Brien JT, Robbins TW, Brooks D, Burn DJ, Barker RA, on behalf of the ICICLE-PD study group. (2014) Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-Parkinson’s disease Study. Brain 137: 2743-58

Wolpe N, Nombela C, Rowe JB. Dopaminergic modulation of positive expectations for goal-directed action: evidence from Parkinson’s disease. Front Psychol (2015)

Zang J, Rittman T, Nombela C, Fois A, Coyle-Gilchrist I, Barker RA, Hughes LE, Rowe JB (2016) Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease. Brain. 139: 161-73.

Ye Z, Rae CL, Nombela C, Ham T, Rittman T, Jones PS, Rodríguez PV, Coyle-Gilchrist I, Regenthal R, Altena E, Housden CR, Maxwell H, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2016). Predicting beneficial effects of atomoxetine and citalopram on response inhibition in Parkinson’s disease with clinical and neuroimaging measures. Hum Brain Mapp 37(3):1026-37

Borchert RJ, Rittman T, Passamonti L, Ye Z, Sami S, Jones SP, Nombela C, Rodríguez PV, Vatansever D, Rae CL, Hughes LE, Robbins TW, Rowe JB (2016). Atomoxetine Enhances Connectivity of Prefrontal Networks in Parkinson's Disease. Neuropsychopharmacology 41(8):2188

Breen DP*, Nombela C*, et al (2016). Hypothalamic volume loss is associated with reduced melatonin output in Parkinson’s disease. Mov Disord 31(7):1062-6

Zhang J, Nombela C, Wolpe N, Barker RA, Rowe JB (2016). Time on Timing: Dissociating Premature Responding From Interval Sensitivity in Parkinson’s Disease. Mov Disord 31(8):1163-72

Rae CL, Nombela C, Rodríguez PV, Ye Z, Hughes LE, Jones PS, Ham T, Rittman T,

 Coyle-Gilchrist I, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2016) Atomoxetine restores the response inhibition network in Parkinson's disease. Brain. 139:2235-48

Nombela C, Fernández S, Castellanos N, Rozas S, Pérez M, Diex G, Moñivas A, Barcia JA (2017) Mindfulness in brain tumor patients may improves anxiety, depression and cognitive performance. Mindfulness 8(6):1725–172

Mejías G, Oliviero A, Barcia JA, Nombela C (2018). Stuttering and levetiracetam: Case report and research proposal. Ann Clin Psychiatry. Feb;30 (1):68-69

Wolpe N, Zhang J, Nombela C, Ingram J, Wolpert D, Cam-CAN, and Rowe JB (2018)  Sensory attenuation in Parkinson’s disease is related to disease severity and dopamine dose. (8), article number: 15643

Nombela C, Lozano A, Villanueva-Iza C, Barcia JA (2019) Simultaneous Stimulation of the Globus Pallidus Interna and the Nucleus Basalis of Meynert in the Parkinson-Dementia Syndrome. Dementia & Geriatric cognitive disorders. 47(1-2):19-28

Avecillas-Chasin J, Alonso-Frech F, Nombela C, Villanueva C, Barcia JA (2019) Stimulation of the tractography-defined subthalamic nucleus regions correlates with clinical outcomes. Neurosurgery. 1; 85(2):E294-E303.

Barcia JA, Avecillas-Chasín JM, Nombela C, Arza R, García-Albea J, Pineda JA, Reneses B, Strange BA (2019). Personalized striatal targets for deep brain stimulation in obsessive-compulsive disorder. Brain Stimulation. 12(3):724-734

Barcia JA, Reneses B, Nombela C (2019). Precision surgery for obsessive compulsive disorder-which is the proper target? Ann Transl Med. Sep; 7(Suppl 6):S184

Giné E, Martínez C, Sanz C, Nombela C, de Castro F (2019) The Women Neuroscientists in the Cajal School. Front Neuroanat. 16;13:72.

Borchert RJ, Rittman T, Rae CL, Passamonti L, Jones SP, Vatansever D, Vázquez-Rodríguez P, Ye Z, Nombela C, Hughes LE, Robbins TW, Rowe JB (2019) Atomoxetine and citalopram alter brain network organization in Parkinson's disease. Brain Commun. 1(1):fcz013

 

Book

Nombela C. (2012) Entrenamiento cognitivo en la enfermedad de Parkinson. Editorial Académica Española. Madrid (Spain), 187 pages

 

Book chapters

Barcia JA; Pérez-Garoz M; Nombela C. 2019. Neuroplasticity and Rewiring of the Brain. In:  Brain Mapping: Indications and Techniques. eds: Alfredo Quiñones-Hinojosa, Kaisorn L. Chaichana and Deependra Mahato. Thieme Medical Publishers, Inc, New York (USA)

Nombela C. (2005). Il Disturbo Ossessivo Compulsivo nell’ Infanzia. In: Psicopatologia Infantile, ed. Guidetti, V. Il Mulino, Roma (Italy).

Fuentes LJ, Fernandez PJ, Nombela C, Martella D. (2009) Atencion y envejecimiento. In: Envejecimiento saludable y alteraciones, eds. Guerrero C, Gomez C, Carpi A, Palmero F. Editorial de la Generalitat de Valencia, Valencia (Spain). Pp 99-118

Barcia C, Ros F, Carrillo MA, Aguado-Llera D, Ros CM, Nombela C, de Pablos V, Fernández-Villalba E, Herrero MT. (2009) Inflammatory response in Parkinsonism. In: Birth, Life and Death of dopaminergic neurons in the substantia nigra  eds. Di Giovanni G, Di Matteo V, Esposito E. Springer, Wien-New York (USA). Pp 159-180

 

Non-Indexed Scientific publications

Nombela C, Sánchez-Gascón F., et al. (2003). Menopausia y Sueño. Enfermería Global (Electronic Journal), nº 4.  www.um.es/eglobal

Nombela C. (2008). Cognitive impairments in Parkinson’s disease. Cognitive evaluation through functional magnetic resonance. Editorial de la Universidad de Murcia (Spain). ISBN: MU-2574-2008/978-84-691-7307-7, 432 pages (available at: http://www.tesisenred.net/handle/10803/10717?show=full)

Nombela C, Nombela M. (2013b) Madurez electroencefalográfica: Estudio de las frecuencias de la región rolándica y sus implicaciones patológicas. Archivos de Neurología, Neuropsiquiatría y Neurocirugía. Vol 2, 210-215

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